JUVÉDERM™ Patient Safety

What Is JUVÉDERM™ Injectable Gel?

As we age, our skin changes. Over time, the natural volume of youthful skin begins to diminish as wrinkles and folds form. But, with Juvéderm™ injectable gel, you don't have to just sit back and let it happen! Recently approved by the FDA, Juvéderm™ injectable gel is a “next-generation” dermal filler. The smooth consistency gel helps to instantly restore your skin's volume and smooth away facial wrinkles and folds, like your "smile lines" or “parentheses” (nasolabial folds—the creases that run from the bottom of your nose to the corners of your mouth).

Juvéderm™ is a smooth consistency gel made of hyaluronic acid—a naturally occurring substance in your skin that helps to add volume and hydration. Your healthcare professional eases Juvéderm™ injectable gel under the skin to provide a smooth, natural look and feel—so everyone will notice (but no one will know)! In fact, studies show superior results of Juvéderm™ compared to a collagen-based dermal filler.* And, almost 90% of all study volunteers who were treated with both Juvéderm™ injectable gel and another dermal filler* preferred Juvéderm™! In addition, Juvéderm™ injectable gel is the first FDA-approved hyaluronic acid dermal filler that is proven to be safe and effective for persons of color.

If you're interested in being treated with this nonsurgical physician-administered treatment option, you should know the advantages of choosing Juvéderm™ injectable gel:

• A "next-generation" filler: JUVÉDERM™ is a “next-generation” non-animal dermal filler that is made from hyaluronic acid—a naturally occurring substance that plays a vital role in hydrating your skin and replenishing its natural volume. No allergy skin tests are needed prior to receiving treatment.
• Advanced technology for long-lasting results: JUVÉDERM™ injectable gel employs its unique manufacturing process to provide the highest concentration of cross-linked hyaluronic acid of any currently available hyaluronic acid dermal filler for long-lasting results. This advanced manufacturing process also creates a smooth consistency gel that flows consistently and easily into the skin and provides a smooth, natural look and feel. Juvéderm™ is the only filler available with this smooth consistency gel formulation—other existing hyaluronic acid fillers are made of granular consistency gels.*

Hyaluronic Acid's Role in the Skin's Appearance

Hyaluronic acid plays an important role in the way your skin looks, feels, and functions. A natural complex sugar found in all mammals, it's a major component of the connective tissue matrix in the dermis—the dense, inner layer of skin beneath the epidermis. This matrix is made up of hyaluronic acid as well as two connective fibers—collagen and elastin.

By its nature, hyaluronic acid retains water like a sponge, absorbing more than 1,000 times its weight. This helps to attract and maintain water within the extracellular space, hydrating your skin and increasing its volume and density. Hyaluronic acid is also involved with the transport of essential nutrients to the skin's viable cells. Hyaluronic acid provides volume, helping to contribute to the skin's overall appearance.

As you age and your skin is exposed to environmental pollutants and the sun's ultraviolet rays, your cells gradually lose the ability to produce hyaluronic acid. Studies have shown that older skin typically has lower levels of hyaluronic acid than younger skin. As you age, your skin tissue becomes dehydrated and the collagen and elastin fibers lose their structure, resulting in a loss of skin volume and the formation of the facial wrinkles and folds that are common characteristics of aged skin.

Hyaluronic acid dermal fillers like Juvéderm™ injectable gel can help to temporarily replace the lost hyaluronic acid and restore your skin's volume and smooth, natural appearance.

JUVÉDERM™ injectable gel offers the highest concentration of cross-linked hyaluronic acid of any currently available hyaluronic acid dermal filler, for results that last up to 6 months or more.